Lumbar puncture (LP) is a type of and relatively safe neurological process. It can be complicated by post-dural puncture frustration (PDPH) after both diagnostic and therapeutic processes. The purpose of this research would be to recognize the occurrence, danger elements and medical characterization of PDPH within the inpatient environment of this main tertiary neurology hospital in Kuwait. We conducted a prospective observational cohort research that included clients who have been admitted to neurology department at Ibn Sina medical center Oncologic treatment resistance , Kuwait, from January 1, 2019 to December 31, 2020, on who, LP had been carried out for diagnostic and/or therapeutic factors. Multivariate logistic regression evaluation was done to guage the organization between PDPH and different medical parameters. A total of 285 clients were included; 225 females (78.9%), mean age of 32.9 ± 11.7years. PDPH had been reported by 84 customers (29.5%), with mean headache start of 1.7 ± 0.8days, and mean timeframe of 2.4 ± 2.1days. The most typical headache kind was lifeless aching in found is independent threat facets for building PDPH. To our understanding, this study represents the very first comprehensive description of PDPH in a population through the Arabian Gulf Region.Findings from clinical rehearse in the main tertiary neurology hospital in Kuwait had been in line with literary works findings. Younger age, feminine sex, reduced BMI, pre-procedural inconvenience, previous reputation for PDPH, and quantity of LP attempts were found becoming separate danger facets for establishing PDPH. To the understanding, this study signifies the first comprehensive information of PDPH in a population through the Arabian Gulf area. Obstetric physical violence is a specific kind of physical violence against women that violates their real human rights. Conducted by obstetric treatment providers in connection with human body and reproductive processes regarding the girl, being described as dehumanized support, punishment of interventionist actions, medicalization, and reversion for the process from natural to pathological. Community based cross-sectional research had been carried out among randomly chosen 661 mothers in Gedeo Zone, South Ethiopia, from May 1 to May 30 2020. Multi-stage sampling technique had been used to have a complete of 661 moms from their kebeles. Information was collected by utilizing face-to–to-face interview with a structured questionnaire and detailed interview has also been utilized. Data entry and evaluation was done by Epi data version 3.1 and SPSS 23.0 statistical software. Bivariate and multivariable logistic regression designs were used to determine kind of obstetric violence that may lead a woman to decide on for house distribution in the place of health facility treatment, this in turn leads to a good boost in maternal morbidity and mortality as sustained by qualitative strategy associated with the research. A hospital-based cross-sectional research design had been carried out from Summer 15 -to July 15, 2021, in North Shewa community hospitals. A complete of 441 moms and newborn pairs were selected by organized random sampling. Information were collected using a pretested and structured interviewer-administered survey with chart reviewing. Information entry and evaluation were done using Epi Data variation 3.1 and Statistical Package for the Social Sciences variation 26 correspondingly. Binary logistic regression was done to must be prioritized for mitigating LBW. Medical care professionals should give attention to testing expectant mothers for intimate companion physical violence, challenging tasks, undernutrition and offering proper treatment during all maternal continuum of treatment may be helpful.This study revealed that the magnitude of low birth fat had been relatively large. Ladies with pregnancy-related problems, grand multiparty, challenging work during pregnancy, intimate lover violence, mid-upper arm circumference lower than 23 cm, and meals insecurity should always be prioritized for mitigating LBW. Health care professionals should consider Screening pregnant women for intimate partner violence, challenging tasks, undernutrition and offering appropriate treatment during all maternal continuum of treatment may be helpful. Medicine resistance is a considerable challenge for chemotherapy in non-small mobile lung disease (NSCLC). Propofol, a commonly made use of intravenous anesthetics, is reported to suppress the malignancy of varied cancers. Nonetheless, the consequences of propofol on cisplatin (DDP) sensitivity in NSCLC and its particular molecular mechanisms have not been clearly clarified yet, and the present research directed to resolve this problem. NSCLC cells were co-treated with propofol and DDP, Cell Counting kit-8 assay, colony development assay and flow cytometry had been conducted to check the part of propofol in controlling Postmortem toxicology DDP-resistance in NSCLC. Next, through carrying out quantitative real-time polymerase sequence response, dual-luciferase gene reporter system and western blot, the responsible molecular axis in propofol managing the DDP susceptibility in NSCLC was uncovered, additionally the function confirmation experiments had been performed by transfection with the inhibitors or small interfering RNAs of these molecules Cerivastatin sodium ic50 .